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Sulfo-SMCC sodium

CAS No. 92921-24-9

Sulfo-SMCC sodium ( —— )

产品货号. M27016 CAS No. 92921-24-9

Sulfo-SMCC 钠是一种常用的异双功能、不可裂解 ADC 交联剂,带有 N-羟基琥珀酰亚胺 (NHS) 酯和马来酰亚胺基团,可分别与伯胺和巯基反应。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥332 有现货
25MG ¥470 有现货
50MG ¥599 有现货
100MG ¥786 有现货
200MG ¥1312 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Sulfo-SMCC sodium
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Sulfo-SMCC 钠是一种常用的异双功能、不可裂解 ADC 交联剂,带有 N-羟基琥珀酰亚胺 (NHS) 酯和马来酰亚胺基团,可分别与伯胺和巯基反应。
  • 产品描述
    Sulfo-SMCC sodium is a commonly used hetero-bifunctional, non-cleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.(In Vitro):The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time.
  • 体外实验
    The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    NF-κB
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    92921-24-9
  • 分子量
    436.37
  • 分子式
    C16H17N2NaO9S
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 125 mg/mL (286.45 mM)
  • SMILES
    [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kim SJ, et al. Antiinflammatory effect of Oldenlandia diffusa and its constituent, hentriacontane, through suppression of caspase-1 activation in mouse peritoneal macrophages. Phytother Res. 2011 Oct;25(10):1537-46.
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