
Sulfo-SMCC sodium
CAS No. 92921-24-9
Sulfo-SMCC sodium ( —— )
产品货号. M27016 CAS No. 92921-24-9
Sulfo-SMCC 钠是一种常用的异双功能、不可裂解 ADC 交联剂,带有 N-羟基琥珀酰亚胺 (NHS) 酯和马来酰亚胺基团,可分别与伯胺和巯基反应。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥332 | 有现货 |
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25MG | ¥470 | 有现货 |
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50MG | ¥599 | 有现货 |
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100MG | ¥786 | 有现货 |
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200MG | ¥1312 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Sulfo-SMCC sodium
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Sulfo-SMCC 钠是一种常用的异双功能、不可裂解 ADC 交联剂,带有 N-羟基琥珀酰亚胺 (NHS) 酯和马来酰亚胺基团,可分别与伯胺和巯基反应。
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产品描述Sulfo-SMCC sodium is a commonly used hetero-bifunctional, non-cleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.(In Vitro):The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time.
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体外实验The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体NF-κB
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研究领域——
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适应症——
化学信息
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CAS Number92921-24-9
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分子量436.37
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分子式C16H17N2NaO9S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (286.45 mM)
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SMILES[Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kim SJ, et al. Antiinflammatory effect of Oldenlandia diffusa and its constituent, hentriacontane, through suppression of caspase-1 activation in mouse peritoneal macrophages. Phytother Res. 2011 Oct;25(10):1537-46.
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