Sulfo-SMCC sodium

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Sulfo-SMCC 钠是一种常用的异双功能、不可裂解 ADC 交联剂，带有 N-羟基琥珀酰亚胺 (NHS) 酯和马来酰亚胺基团，可分别与伯胺和巯基反应。

Sulfo-SMCC sodium is a commonly used hetero-bifunctional, non-cleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.(In Vitro):The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time.

The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time.

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Others

Other Targets

NF-κB

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92921-24-9

436.37

C16H17N2NaO9S

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (286.45 mM)

[Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)C2CCC(CN3C(=O)C=CC3=O)CC2)C1=O

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(-20℃)

With Ice Pack

≥ 2 years